In early summer, CPSR invited collaborative proposals focused on optimizing the dose and timing of sensory-motor rehabilitation and recovery interventions following stroke. The goal: To address fundamental unanswered questions through collaborative proof-of-principle studies. Both preclinical (basic) and clinical research were encouraged, provided a clear rationale was included as to potential translational impact of the research for people living with stroke. 
 
Four awards of approximately $200,000 each have just been awarded. The time period for conducting the research is October 2019 to March 2022 (2.5 years).

Recipients of the 2019 CPSR Collaborative Grant Competition – Dose & Timing 

1. Optimizing the timing of priming exercise to boost motor learning and enhance motor and cognitive recovery from stroke 

Project Leaders/Principal Investigators: Drs. Lara Boyd, University of British Columbia and Michelle Ploughman, Memorial University of Newfoundland 

Co-investigators: Dr. Gail Eskes (Dalhousie University), Dr. Jason McCarthy (MUN), Dr. Courtney Pollock (UBC), Dr. Kristin Campbell (UBC), Dr. Brian Greeley (UBC) 

Brief Project Description: The main objectives are to determine whether aerobic exercise “primes” the brain for recovery early after stroke and whether this priming in combination with therapy can benefit motor learning, cognitive and motor function after stroke. 

2. Determining Optimal post-Stroke Exercise (DOSE) Stepped-Wedge Randomized Controlled Trial 

Project Leader & Principal Investigator: Dr. Janice Eng, University of British Columbia 

Co-investigators: Dr. Sean Dukelow (University of Calgary), Dr. Mark Bayley (Toronto Rehabilitation Institute –University Health Network), Dr. Jennifer Yao (UBC), Dr. Krista Best (Université Laval), Dr. Brodie Sakakibara (UBC, Okanagan Site), Dr. Hubert Wong (UBC), Dr. Tara Klassen (UBC), Dr. Sue Peters (UBC),  Dr. Louise Connell (University of Central Lancashire).

Brief Project Description: The primary objective is to determine the effect of the DOSE protocol in improving the primary outcome of walking in stroke patients over the hospital rehabilitation period. Secondary outcomes will be evaluated and include motor recovery and quality of life. 

3. Determining the optimal dose of reactive balance training after stroke – a pilot study 

Project Leaders/Principal Investigators: Drs. Avril Mansfield and Elizabeth Inness, Toronto Rehabilitation Institute –University Health Network 

Co-investigators: Dr. Tanvi Bhatt (University of Illinois), Dr. Andrew Huntley (TRI–UHN

Collaborators: Katherine Dittmann (St John’s Rehab – Sunnybrook Health Sciences Centre), Katherine Mileski (TRI–UHN), Jennifer Neirinckx (TRI–UHN

Brief Project Description: This study will inform physiotherapists and their patients about the optimal dose of reactive balance training for people with stroke who are attending rehabilitation. 

4. Optimized Rehabilitation Dose to Enhance Recovery (ORDER): A Preclinical and Clinical Collaborative Research Pipeline 

Project Leader & Principal Investigator: Dr. Greg Silasi, University of Ottawa 

Co-investigators: Dr. Dale Corbett (University of Ottawa), Dr. Kathryn Hayward (University of Melbourne), Dr. Matthew McDonald (University of Ottawa

Collaborators: Matthew Jeffers (University of Ottawa), Leonid Churilov (University of Melbourne), Emily Dalton (University of Melbourne

Brief Project Description: This study will determine the optimal dose of rehabilitation to improve recovery by systematically varying the amount of reaching practice, the number of sessions per day, and the duration of therapy, across two types of reaching practice and we will determine whether this dose is effective early after stroke, as well as much later when recovery is perceived to slow down.

 

 

2018 CPSR Collaborative Innovation Grant Competition Recipients and 2018 CPSR Trainee Awards Winners: https://mailchi.mp/e3db13c513e8/canadian-stroke-recovery-news-august-2018

2017 Catalyst Grant and Implementation Science Grant winners:

2017-CPSR-Catalyst-Implementation-Science-Grant-Winners-with-mini-blurbs.pdf

2017 CSPR-REPAR Catalyst Grant winners:

2017-CPSR-REPAR-Catalyst-Grant-Winners-with-mini-blurbs.pdf

2016 Catalyst Grant winners:

2016-CPSR-Trainee-Award-Winners-with-blurbs-mini.pdf

Past Catalyst Grant winners:

Past-Catalyst-Grant-winners.pdf

CaSTOR grants:

Canadian Stroke Trials for Optimized Results (CaSTOR) is a joint initiative of the Canadian Stroke Consortium and the HSF Canadian Partnership for Stroke Recovery. The top-ranked CaSTOR grant in 2017 was awarded to CanStim, a national initiative to develop guidelines and test brain stimulation to boost recovery.

Read the full list of award winners 2017-CaSTOR awards

Telerehabilitation grants:

In February 2013, CPSR announced a $1.3-million national initiative to deliver “telerehabilitation” to the homes of more than 200 people living with stroke in at least 10 Canadian cities — the first step towards improving access to desperately needed stroke-recovery services. Researchers in Nova Scotia, P.E.I., Quebec, Ontario, Manitoba and British Columbia were awarded funds to test innovative ways to provide physical, occupational and speech therapy and lifestyle coaching to people who are recovering at home after a stroke. The telerehab initiative is a joint effort of Heart & Stroke and the Canadian Partnership for Stroke Recovery. Researchers are publishing a lessons-learned report on their findings and a toolkit for other investigators.

Read the full list of telerehabilitation projectsTelerehehabilitation projects .docx