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Research

Platforms

CPSR PLATFORMS

CPSR has three platform infrastructures that may be of benefit to researchers and trainees. The three CPSR platforms are:

1) Animal Stroke Model & Behaviour Testing and Preclinical Brain Imaging Facility
An animal behaviour core facility is available at the University of Ottawa. The facility has state-of-the-art automated equipment allowing for efficient and reproducible data collection. Novel animal models developed by the group include a mouse stroke model for photothrombosis, and a 7.0 Tesla MRI facility is available for high resolution imaging of stroke damage in animals.

2) Human Brain Imaging Analysis Pipeline
Brain imaging analysis pipelines are important for stroke researchers trying to investigate brain-behaviour relationships in cross-sectional or longitudinal analyses. This platform, developed over the past 10 years, uses a standardized clinically practical imaging protocol to provide reliable and efficient quantifiable data of both structural and functional human brain damage to be used in analyses.

3) Stroke Rehabilitation Clinical Trial Infrastructure
This platform was created to develop a network of partnerships (affiliations) with rehabilitation institutes to improve patient recruitment and expand capacity to implement translational studies. Future CPSR stroke rehabilitation clinical trials will be able to build upon infrastructure developed through this platform, including standardized assessment batteries, tablet-based data entry system, interprofessional relationships, as well as data mining natural stroke recovery profile data on more than 500 stroke patients.

Each platform is a shared CPSR resource available to all CPSR researchers and should be considered when designing your projects. There are multiple ways to benefit from using these shared platforms, including directly (e.g., project data mining, data management, imaging analysis) and indirectly (e.g., experimental training, advice and guidance).

For questions about CPSR platforms, including how to utilize these shared resources, please email Farrell Leibovitch, CPSR Director Research and Training Programs at farrell@canadianstroke.ca