Dr. Meltzer’s research deals with the neural mechanisms responsible for understanding and producing language, with an emphasis on multiple partially redundant pathways. The study of multiple pathways for information processing is essential to future developments in stroke rehabilitation, as functional and structural assessments can be made of an individual’s capacity to exploit spared pathways to recover cognitive and linguistic abilities. Behavioural intervention strategies could be tailored to an individual’s post-stroke neuroanatomical status for maximal effect. Furthermore, physiological interventions such as noninvasive brain stimulation (NIBS) can be targeted and optimized for individuals to bring about the desired recruitment of brain networks to achieve functional restoration and compensation.
His work has explored the potential of magnetoencephalography (MEG) as a mapping tool in neurolinguistics, providing the spatial and temporal resolution necessary to measure the involvement of specific neural pathways on a time scale relevant to everyday language use. In current work, his team is using MEG to evaluate the brain’s response to transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (TDCS), two techniques that may help promote beneficial plasticity in recovery from brain injury, but are as yet poorly understood.